Phone number icon

REQUEST A BROCHURE

Sign up for newsletter

Image of Cruise from Guayaquil to San Juan
The Americas & Caribbean

Guayaquil

San Juan

FARES FROM was $4,800

Offer icon

now

$4,215

per guest *

save up to 15% per room or suite

depart

Sep 5, 2026

arrive

Sep 14, 2026

9 NIGHTS

ABOARD
Previous

San Diego - Guayaquil

Next

San Juan - New York City

5 countries
7 ports
Sail along one of the world’s manmade wonders, the Panama Canal, on this cruise departing Guayaquil. We’ll relax into life onboard with two days at sea, crossing from South to Central America at Fuerta Amador for Panama City, where we’ll spend two nights. That’s plenty of time to explore its streets, old and new, venture to its fringe of beaches and jungle – and, of course, buy a Panama hat. You could also take a closer look at the canal locks at Miraflores, through which gigantic vessels squeeze onto the canal. It’s time now for our ship to slip along the narrow channel built more than a century ago to push back nature for 52 miles to join the Pacific and Atlantic Oceans. At the other end, we make for Cartegena, on the coast of Colombia, with a beauty of an old city that is recognised by UNESCO. Then we cross the Caribbean to two equally historic cities, Santo Domingo in the Dominican Republic and, via the holiday playground of Punta Cana, our final port, San Juan in Puerto Rico.
Itinerary map

Itinerary

the galapágos - inside nature's laboratory
Extension The Galapágos - Inside Nature's Laboratory picture
pre cruise extensions

The Galapágos - Inside Nature's Laboratory

8 days

See the the tranquil backwaters of the Galapágos archipelago. This expert-led tour offers an in-depth view of the islands, the living natural laboratory that inspired Charles Darwin's theory of evolution.


Highlights

  • Go island-hopping cruise around the Galapágos
  • Discover the story of Charles Darwin on the islands.
  • Savor exceptional Relais Châteaux dining and hospitality onboard, an A&K exclusive in the Galápagos Islands

price from $13,900

01.

Guayaquil, Ecuador

sep 05, 2026

departure 7:00 PM

Guayaquil, Ecuador picture
To most seasoned travelers, Guayaquil is known for being the gateway to the Galapagos Islands. However, there's much to appreciate and enjoy about the “Pacific Pearl” all on its own. The Malecon 2000 is the beating heart and signature feature of this city. Running along the Guayas River, this promenade offers up lovely green spaces, shops and boutiques, museums, a wide variety of restaurants, handicraft market, and all kinds of entertainment options. Cast your gaze up toward the distant hills and you'll see Las Peñas, the picturesque, barrio dotted with brightly colored houses. You'll also want to look up into the trees at the Parque Seminario, where you'll spot iguanas wisely waiting out the heat of the day in the shade.

02.

Day at sea

sep 06, 2026

Photo not available

Image of Day at sea

03.

Fuerte Amador, Panama

sep 07, 2026

arrival 7:00 PM

Overnight

1 EXCURSION

Fuerte Amador, Panama picture
Once a defensive complex guarding the Panama Canal's entrance, Fuerte Amador now serves as a portal to Panama's fascinating past. Pay a visit to the Miraflores Visitors Center for an interactive look at the canal's history, operations, and global significance, or discover the Frank Gehry-designed Biomuseo, which celebrates Panama's biological and cultural diversity. From Fuerte Amador, it's a short trip into bustling Panama City, with its cobblestoned Casco Viejo district and colonial-era architecture. Taste your way around this UNESCO-recognized City of Gastronomy, sampling everything from fresh ceviche to golden empanadas, before finding tranquility in the Metropolitan Natural Park, the only tropical forest located within a capital city in Latin America.

there are 1 optional shore excursions at this port

04.

Fuerte Amador, Panama

sep 08, 2026

Overnight

10 EXCURSIONS

Fuerte Amador, Panama picture
Once a defensive complex guarding the Panama Canal's entrance, Fuerte Amador now serves as a portal to Panama's fascinating past. Pay a visit to the Miraflores Visitors Center for an interactive look at the canal's history, operations, and global significance, or discover the Frank Gehry-designed Biomuseo, which celebrates Panama's biological and cultural diversity. From Fuerte Amador, it's a short trip into bustling Panama City, with its cobblestoned Casco Viejo district and colonial-era architecture. Taste your way around this UNESCO-recognized City of Gastronomy, sampling everything from fresh ceviche to golden empanadas, before finding tranquility in the Metropolitan Natural Park, the only tropical forest located within a capital city in Latin America.

there are 10 optional shore excursions at this port

05.

Fuerte Amador, Panama

sep 09, 2026

departure 4:00 AM

Fuerte Amador, Panama picture
Once a defensive complex guarding the Panama Canal's entrance, Fuerte Amador now serves as a portal to Panama's fascinating past. Pay a visit to the Miraflores Visitors Center for an interactive look at the canal's history, operations, and global significance, or discover the Frank Gehry-designed Biomuseo, which celebrates Panama's biological and cultural diversity. From Fuerte Amador, it's a short trip into bustling Panama City, with its cobblestoned Casco Viejo district and colonial-era architecture. Taste your way around this UNESCO-recognized City of Gastronomy, sampling everything from fresh ceviche to golden empanadas, before finding tranquility in the Metropolitan Natural Park, the only tropical forest located within a capital city in Latin America.

Panama Canal Transit, Panama

sep 09, 2026

Panama Canal Transit, Panama picture
The Panama Canal famously connects the Pacific Ocean with the Caribbean Sea. It began its activity in 1914, quickly becoming a crucial waterway for maritime trade. While traversing this iconic waterway, you can admire the glorious natural landscapes, which are just 15 minutes away from Panama City.

06.

Cartagena, Colombia

sep 10, 2026

10:00 AM - 7:00 PM

8 EXCURSIONS

Cartagena, Colombia picture
Lose yourself in the beautiful chaos of Cartagena, where layers of cultural influence intersect to create a city rich in character. The walled Old Town – established in the 16th century and now a UNESCO World Heritage site – is best explored on foot. Stop by a street stall for fresh lulo juice before setting off to explore the labyrinthine streets, filled with shady plazas, ornate former mansions, and balconies overflowing with flowers. Just outside the historic walls, you'll find the colorful neighborhood of Getsemaní, where vivid murals adorn the facades of shops and galleries, and salsa music wafts from lively bars.

there are 8 optional shore excursions at this port

07.

Day at sea

sep 11, 2026

Photo not available

Image of Day at sea

08.

Santo Domingo, Dominican Republic

sep 12, 2026

8:00 AM - 7:00 PM

4 EXCURSIONS

Santo Domingo, Dominican Republic picture
Capital of the Dominican Republic, Santo Domingo is a place full of color, history and culture. Learn about its rich colonial heritage by visiting the university, the cathedral and the historic Hospital San Nicolas de Bari in the UNESCO-listed neighborhood of Colonial City, but also save time to relax on its incredible beaches.

there are 4 optional shore excursions at this port

09.

Punta Cana, Dominican Republic

sep 13, 2026

8:00 AM - 6:00 PM

Anchor

5 EXCURSIONS

Punta Cana, Dominican Republic picture
Coconut palms, sugar-soft sand, crystalline waters teeming with fish – the eastern tip of this island is bliss for beach lovers, made even better with the Dominicans' slow-paced charm. There are so many ways to explore, from dune-buggy rides through ancient palm groves to eco-friendly walking trails in Bavaro Park, and encounters with some of the 150 animal species – including iguanas, dolphins, sea lions, and parrots – that call Manati Park home. The 500-year-old town of Higuey is the place to browse for souvenirs, shop for colorful ceramics and textiles in the lively Municipal Market, and sample a wicked mamajuana rum cocktail (or two).

there are 5 optional shore excursions at this port

10.

San Juan, Puerto Rico

sep 14, 2026

arrival 7:00 AM

San Juan, Puerto Rico picture
Puerto Rico's capital makes a strong impression – even before you arrive on shore. Sailing into the harbor, keep an eye out for El Morro, a 16th-century citadel and UNESCO World Heritage Site, Castillo San Cristobal, a fearsome fortress built to scare away invaders, and La Fortaleza, the impressive official residence of the Governor of Puerto Rico. Once ashore, step back in time along cobbled streets and through squares flanked by pastel-colored Spanish colonial buildings. Or take your pick of beaches – will it be the golden-sanded Isla Verde, the snorkeler-approved El Escambrón, or the laid-back Ocean Park? Just don't leave San Juan without sampling a piña colada (or two) – the tropical cocktail was invented here in the 1950s.

Previous

San Diego - Guayaquil

Next

San Juan - New York City

Save & Indulge
Offer tag iconoffer | expires May 31, 2026

EXCEPTIONAL SAVINGS

We're offering up to 30% savings on select 2026, 2027, and 2028 sailings. Book by May 31, 2026.

*Terms and conditions apply.

caribbean
Offer tag iconoffer | expires May 31, 2026

CARIBBEAN INCLUDED AIR

Caribbean Included Air has been extended, with more voyages now eligible. Book one of our select Caribbean sailings and you will receive up to $3,000 per guest room or suite towards flights plus transfers when you book your travel with us, or up to $2,000 credit per guest room or suite towards your cruise if you arrange your own flights.

*Terms and conditions apply

SO LOW SOLO
Offer tag iconoffer | expires May 31, 2026

SO LOW SOLO

Enjoy the luxury of a Sapphire or Aquamarine Veranda Suite all to yourself with a reduced solo supplement of just 25% on select 2026 and 2027 voyages.

*Terms and conditions apply

sort by

DOUBLE GUEST ROOM WITH OCEAN VIEW

SUITE SIZEUP TO 215 SQ FT
DECK8, 7, 5
LOCATIONMID/AFT
EXCEPTIONAL SAVINGS

save up to 15% per room or suite

was $4,800Offer icon 
now$4,215

DOUBLE GUEST ROOM WITH VERANDA

SUITE SIZEUP TO 215 SQ FT
BALCONY SIZEUP TO 54 SQ FT
DECK9, 8
LOCATIONFWD, MID/AFT
regular fare

Fares per guest starting from

$5,700

SINGLE GUEST ROOM WITH OCEAN VIEW

SUITE SIZEUP TO 215 SQ FT
DECK7
LOCATIONFWD
EXCEPTIONAL SAVINGS

save up to 10% per room or suite

was $6,400Offer icon 
now$5,850

SO LOW SOLO

AQUAMARINE VERANDA SUITE

SUITE SIZEUP TO 323 SQ FT
BALCONY SIZEUP TO 86 SQ FT
DECK10, 9
LOCATIONFWD, MID/AFT
EXCEPTIONAL SAVINGS

save up to 10% per room or suite

was $6,600Offer icon 
now$6,030

SAPPHIRE OCEAN VIEW SUITE

SUITE SIZEUP TO 430 SQ FT
DECK8, 7, 5
LOCATIONMID/AFT
EXCEPTIONAL SAVINGS

save up to 15% per room or suite

was $7,000Offer icon 
now$6,085

SO LOW SOLO

SAPPHIRE VERANDA SUITE

SUITE SIZEUP TO 430 SQ FT
BALCONY SIZEUP TO 107 SQ FT
DECK10, 9, 8
LOCATIONFWD, MID/AFT
EXCEPTIONAL SAVINGS

save up to 10% per room or suite

was $8,400Offer icon 
now$7,650

JUNIOR CRYSTAL PENTHOUSE SUITE

SUITE SIZEUP TO 645 SQ FT
BALCONY SIZEUP TO 161 SQ FT
DECK9, 8
LOCATIONFWD
regular fare

Fares per guest starting from

$13,800

CRYSTAL PENTHOUSE SUITE

SUITE SIZEUP TO 909 SQ FT
BALCONY SIZEUP TO 107 SQ FT
DECK10, 8
LOCATIONMID/AFT
regular fare

Fares per guest starting from

$17,000

An Exclusive All-Inclusive Experience

On Crystal ships, our all-inclusive program gives you the sense of freedom and peace of mind that comes from knowing we’ve taken care of everything.

Dining & Beverages
  • Curated selection of wines, champagne, spirits, & soft drinks
  • Multiple dining options to explore
  • 24-hour in-suite dining service
  • At least one complimentary reservation at the only Nobu restaurant at sea, Umi Uma, and Osteria d’ Ovidio
  • Personalized Service & Comfort
  • Dedicated butler service in every suite and guest room
  • Complimentary unlimited Wi-Fi
  • All tips and gratuities included
  • Wellness, Recreation & Entertainment
  • A wide variety of onboard activities, including paddle tennis, pickleball, and golf driving nets
  • Access to spa facilities and a fully equipped fitness centre
  • Evening entertainment ranging from dazzling Broadway-style shows to inspiring TED-style talks
  • Discover

    Crystal Symphony

    With elegant lines and sweeping ocean views, our intimate ship houses expansive suites and guest rooms, alongside a world-class choice of dining, wellness and entertainment.

    REFURBISHED IN

    2025

    GUEST CAPACITY

    606

    OCEAN-VIEW ROOMS AND SUITES

    330

    DINING VENUES

    9

    Our 9 Exceptional Restaurants

    Onboard Experiences

    Sumptuous suites, the finest cuisine, Broadway-standard entertainment, and a soothing spa – your every wish is granted.

    suites & service image

    suites & service

    Warm, intuitive service, spacious and comfortable suites and social areas… all that’s left for you to do is relax.

    food & drink image

    food & drink

    Unparalleled choice, including the only Nobu restaurant at sea, makes dining aboard Crystal unforgettable.

    entertainment image

    entertainment

    From Broadway-themed shows and comedy to live music and lectures, we have a world of options to keep you amused.

    aurōra spa image

    aurōra spa

    Refresh mind and body with the wellbeing benefits of our indulgent treatments. Or just relax with a purifying sauna.

    Entertainment on this Ship

    Heino Klinck

    Heino Klinck

    Lecturer, World Affairs

    Ed Larson

    Ed Larson

    Lecturer, Destinations

    Ed Larson holds a Ph.D. in the History of Science, a Harvard law degree, and a Pulitzer Prize and has authored fifteen books.

    Extend the Extraordinary with Our Sister Company Abercrombie & Kent

    Extension Peru: Machu Picchu and Amazon Cruise picture
    Abercrombie and Kent logo
    Small Group Journeys
    peru: machu picchu and amazon cruise

    max guests 18

    price from $16,795

    length 13 days

    Spanning the soaring stone walls of Machu Picchu and the remote reaches of the Peruvian rainforest, this exhilarating Peruvian adventure combines two bucket-list destinations in one incredible journey. First, explore the Sacred Valley with llamas at your side and discover the wonders of Machu Picchu. Then, cruise the Amazon Basin aboard Pure Amazon, an A&K Sanctuary, the region’s finest riverboat.

    your cruise

    embark — Sep 5

    Guayaquil

    disembark — Sep 14

    San Juan

    Peru: Machu Picchu and Amazon Cruise

    Aug 21 - Sep 2

    Lima

    2 days

    Cusco

    3 days

    Sacred Valley

    1 day

    Machu Picchu

    2 days

    Nauta

    5 days

    Extension The Galapágos - Inside Nature's Laboratory picture
    Pre Cruise Extensions
    the galapágos - inside nature's laboratory

    price from $13,900

    length 8 days

    See the the tranquil backwaters of the Galapágos archipelago. This expert-led tour offers an in-depth view of the islands, the living natural laboratory that inspired Charles Darwin's theory of evolution.


    Highlights

    • Go island-hopping cruise around the Galapágos
    • Discover the story of Charles Darwin on the islands.
    • Savor exceptional Relais Châteaux dining and hospitality onboard, an A&K exclusive in the Galápagos Islands

    8-days The Galapágos - Inside Nature's Laboratory

    Aug 28 - Sep 5

    Guayaquil

    1 day

    San Cristobal Island

    1 day

    Prince Philips Step's, Genovesa

    1 day

    Santa Cruz Highlands

    1 day

    Punta Espinoza, Fernandina

    2 days

    Puerto Egas

    1 day

    Charles Darwin Station

    1 day

    your cruise

    embark — Sep 5

    Guayaquil

    disembark — Sep 14

    San Juan

    Featured Excursions for this Voyage

    Take in breathtaking views from above, sharpen your skills in a hands-on class, or unwind with one-of-a-kind experiences. Whether you seek adventure, relaxation, or both, our Shore Excursions deliver it all

    Shore excursion image of Panoramic Panama
    excursions

    Panoramic Panama

    Fuerte Amador (Panama City)
    Shore excursion image of Birdwatching at Colombia National Aviary
    excursions

    Birdwatching at Colombia National Aviary

    Cartagena
    Shore excursion image of Hands-On Dominican Chocolate Experience
    excursions

    Hands-On Dominican Chocolate Experience

    Santo Domingo

    Similar Cruises

    Map of The Americas & Caribbean
    The Americas & Caribbean

    Fort Lauderdale

    Fort Lauderdale

    DEPART

    Dec 30, 2026

    ARRIVE

    Jan 10, 2027

    11 Nights Aboard

    Fares per guest from

    $5,800
    Map of The Americas & Caribbean
    The Americas & Caribbean

    Fort Lauderdale

    Fort Lauderdale

    DEPART

    Dec 20, 2026

    ARRIVE

    Jan 10, 2027

    21 Nights Aboard

    Fares per guest from

    $11,800
    Map of The Americas & Caribbean
    The Americas & Caribbean

    Fort Lauderdale

    Fort Lauderdale

    DEPART

    Feb 12, 2028

    ARRIVE

    Mar 10, 2028

    27 Nights Aboard

    Fares per guest from

    $13,000
    Map of The Americas & Caribbean
    The Americas & Caribbean

    Fort Lauderdale

    Cartagena

    DEPART

    Feb 12, 2028

    ARRIVE

    Feb 29, 2028

    17 Nights Aboard

    Fares per guest from

    $8,000

    Stories

    Get our 2026-2027 Caribbean & South American E-brochure

    CARIBBEAN & SOUTH AMERICAN EDIT

    CARIBBEAN & SOUTH AMERICAN EDIT

    VOYAGES 2026-2027