Phone number icon

REQUEST A BROCHURE

Sign up for newsletter

Image of Cruise from Lisbon to Istanbul
Europe & Mediterranean

Lisbon

Istanbul

14 NIGHTS

FARES FROM

  per guest *

depart

Mar 31, 2025

arrive

Apr 14, 2025

ABOARD Crystal Serenity
0 ports
14 nights
Set sail for a generous helping of history on this voyage from Lisbon to Istanbul. First, we head south on a sea day to Cadiz in Spain for a tour of its historic heart, and continue eastwards to Málaga, Cartegena, and Valencia, before another day at sea. An overnight in Valletta on Malta offers the chance to see St. John`s Cathedral and its two Caravaggio masterpieces, and two Greek islands, Crete and Rhodes, offer serious archaeological study. Our voyage ends with a glimpse of Ottoman times in Istanbul.
Itinerary map

Itinerary

An Exclusive All-Inclusive Experience

On Crystal ships, our all-inclusive program gives you the sense of freedom and peace of mind that comes from knowing we’ve taken care of everything.

Dining & Beverages
  • Curated selection of wines, champagne, spirits, & soft drinks
  • Multiple dining options to explore
  • 24-hour in-suite dining service
  • At least one complimentary reservation at the only Nobu restaurant at sea, Umi Uma, and Osteria d’ Ovidio
  • Personalized Service & Comfort
  • Dedicated butler service in every suite and guest room
  • Complimentary unlimited Wi-Fi
  • All tips and gratuities included
  • Wellness, Recreation & Entertainment
  • A wide variety of onboard activities, including paddle tennis, pickleball, and golf driving nets
  • Access to spa facilities and a fully equipped fitness centre
  • Evening entertainment ranging from dazzling Broadway-style shows to inspiring TED-style talks
  • Discover

    Crystal Serenity

    With an industry-leading space to guest ratio across an array of social areas, Crystal Serenity offers the utmost comfort, quality, personalization and choice.

    REFURBISHED IN

    2023

    GUEST CAPACITY

    740

    OCEAN-VIEW ROOMS AND SUITES

    402

    DINING VENUES

    10

    Our 9 Exceptional Restaurants

    Onboard Experiences

    Sumptuous suites, the finest cuisine, Broadway-standard entertainment, and a soothing spa – your every wish is granted.

    suites & service image

    suites & service

    Warm, intuitive service, spacious and comfortable suites and social areas… all that’s left for you to do is relax.

    food & drink image

    food & drink

    Unparalleled choice, including the only Nobu restaurant at sea, makes dining aboard Crystal unforgettable.

    entertainment image

    entertainment

    From Broadway-themed shows and comedy to live music and lectures, we have a world of options to keep you amused.

    aurōra spa image

    aurōra spa

    Refresh mind and body with the wellbeing benefits of our indulgent treatments. Or just relax with a purifying sauna.

    Extend the Extraordinary with Our Sister Company Abercrombie & Kent

    Extension TIMELESS CAPPADOCIA picture
    Overland Adventures by A&K
    timeless cappadocia

    price from $3,999

    length 3 days

    Gliding silently over the fairy chimneys and rock-face churches of Cappadocia in a hot-air balloon as the sun rises is one of Europe's top bucket-list experiences, and this excursion gives you the chance to do just that. Not a fan of heights? Go deep instead, traversing the network of caves beneath this extraordinary landscape.

    HIGHLIGHTS:

    • Optional hot-air-balloon ride over Cappadocia
    • Explore the intricate network of tunnels of Kaymakli Underground City
    • Enjoy lunch with a local family in their home for an authentic cultural experience
    • Try your hand at the potter's wheel in an artisan's studio

    your cruise

    embark — Mar 31

    Lisbon

    disembark — Apr 14

    Istanbul

    3-days Overland Adventures by A&K

    Cappadocia

    3 days

    Similar Cruises

    Map image of the given destination.

    Map of Europe & Mediterranean
    Europe & Mediterranean

    Barcelona

    Monte Carlo

    3 Nights

    Fares from $2,700 per guest *

     

    DEPART

    Aug 21, 2026

    ARRIVE

    Aug 24, 2026
    Aboard Crystal Symphony
    Map image of the given destination.

    Map of Europe & Mediterranean
    Europe & Mediterranean

    Lisbon

    Athens Piraeus

    32 Nights

    Fares from $23,600 per guest *

     

    DEPART

    Aug 14, 2026

    ARRIVE

    Sep 15, 2026
    Aboard Crystal Symphony
    Map image of the given destination.

    Map of Europe & Mediterranean
    Europe & Mediterranean

    Barcelona

    Palma de Mallorca

    6 Nights

    Fares from $4,300 per guest *

     

    DEPART

    Jun 15, 2026

    ARRIVE

    Jun 21, 2026
    Aboard Crystal Symphony
    Map image of the given destination.

    Map of Europe & Mediterranean
    Europe & Mediterranean

    Palma de Mallorca

    Lisbon

    6 Nights

    Fares from $4,400 per guest *

     

    DEPART

    Jun 21, 2026

    ARRIVE

    Jun 27, 2026
    Aboard Crystal Symphony

    Stories

    Get our 2026 Mediterranean E-brochure

    crystal cruises e-brochure mediterranean

    THE MEDITERRANEAN EDIT

    2026 VOYAGES